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KMID : 0388220110180030212
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Journal of the Korean Rheumatism Association
2011 Volume.18 No. 3 p.212 ~ p.215
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A Case of Invasive Pulmonary Aspergillosis in a Patient with Rheumatoid Arthritis Treated with Adalimumab
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Kim Jae-Hee
Bae Joong-Gi
Jun Jae-Wan
Lee Hyun-Sung
Ju Hyung-Wook
Oh Ji-Seon
Choi Seung-Won
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Abstract
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We describe a fatal case of invasive pulmonary aspergillosis in a patient with rheumatoid arthritis receiving the TNF-? inhibitor, adalimumab. The use of TNF-? inhibitor has been associated with an increased risk of infections, including tuberculosis and other opportunistic infections. Physicians should have a high index of suspicion for opportunistic infection that can develop during TNF-? inhibitor treatment.
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KEYWORD
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Invasive aspergillosis, Rheumatoid arthritis, Tumor necrosis factor-alpha
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